Embracing others, despite cultural differences, is a key aspect of Star Trek’s message and enduring legacy. Though Gene Roddenberry was loathe to include any sort of strife, negativity, or conflict among crew members in his scripts, there have nonetheless been some superior character relationships that blossom from early dislike.
In The Original Series, Spock and McCoy quickly despised one another’s perspectives and mentality, but over time, despite (or because of) the many arguments between them, mutual admiration and respect starts to underpin their association. Julian Bashir and Miles O’Brien are good examples of this phenomenon as well. The grizzled, business-like chief found Bashir’s outgoing and excitable nature almost intolerable, but sharing in danger and serving together for a period of time sees them grow into acquaintances, than friends, then inseparable brothers.